Top 8 Courier Service Companies in San Francisco [2025]

Introduction

San Francisco is not just a hub for startups and tech giants; it is a city built on urgency, precision, and reliability. With its steep streets, diverse neighborhoods, and an economy that runs 24/7, the demand for dependable courier services in San Francisco is higher than ever. From transporting sensitive legal documents to time-critical medical sample transfers between UCSF Medical Center and research labs, every delivery counts.

Businesses across the San Francisco Bay Area increasingly rely on courier solutions that offer both speed and flexibility. And with customer expectations soaring, choosing the right day courier service is mission-critical. Whether you are a legal firm requiring court filings at the Superior Court, a health facility handling stat medical deliveries, or a retail business ensuring next-day fulfillment, the right courier service can define your brand experience.

Key highlights on San Francisco courier services:

• Legal courier services are in high demand due to proximity to district court and criminal justice court locations.

• Medical couriers play a crucial role in equipment deliveries and stat medical logistics across Greater San Francisco.

• Same-day delivery services are shaping customer loyalty for e-commerce and B2B.

• Delivery drivers and box trucks must navigate tough traffic, especially during rush hour in downtown San Francisco, CA.

• Tech-integrated platforms like Senpex and Uber Direct are streamlining the delivery process.

Top 8 Courier Service Companies in San Francisco [2025]

With logistics pressure mounting and customer expectations rising, finding a reliable courier service in San Francisco CA, is no small task. Below, we review the best day courier providers helping local businesses deliver packages efficiently and professionally.

1. DHL Express

DHL Express remains one of the most globally trusted names for international and domestic deliveries. In San Francisco, their service network covers every major district, offering unmatched speed for cross-border shipping. Businesses with overseas clientele trust DHL for its robust customs handling and door-to-door commitments.

Services & features:

• Time-definite international delivery with customs clearance.

• Same-day delivery service for local and high-priority shipments.

• GoGreen Plus initiative to offset carbon emissions.

• Real-time tracking and digital proof of delivery.

Rates: Pricing varies by destination, weight, and urgency. You can get a quote instantly through their site or by phone. Expect custom pricing for same-day services.

2. FedEx

FedEx is widely regarded as a comprehensive courier option for both domestic and international logistics. In San Francisco, FedEx services cater to businesses needing overnight and two-day solutions, especially those requiring legal courier documentation or medical equipment delivery.

Services & features:

• Express Overnight, 2-Day, and Ground services.

• FedEx Freight for bulky shipments.

• Hold-at-location for added security.

• Integration with e-commerce platforms.

Rates: FedEx implemented a 5.9% GRI in 2025. Local deliveries in San Francisco range from $10 to $40 for smaller packages. Specialized courier services cost extra.

3. UPS

UPS continues to lead in reliable courier services across San Francisco, CA. From downtown offices to neighborhoods near UCSF Benioff Hospital, UPS offers scalable logistics options. Their large fleet handles business day deliveries, stat medical deliveries, and legal documents with equal precision.

Services & features:

• Next Day Air and 2nd Day Air.

• UPS My Choice for delivery scheduling.

• Specialized medical couriers with cold-chain handling.

• Court filings and legal deliveries within the city.

Rates: Rates start at $8.75 for UPS Ground. Additional charges for fuel, residential delivery, and box truck requirements may apply.

4. OnTrac

Now merged with LaserShip, OnTrac is redefining last-mile courier services in the Bay Area. Known for e-commerce fulfillment and next-day solutions, OnTrac supports flexible cut-off times and a 7-day network, making it ideal for high-volume businesses.

Services & features:

• Same-day delivery in the greater Bay Area.

• Ground Switcher program for optimized transit.

• Parcel tracking through API integration.

• Delivery to both commercial and residential destinations.

Rates: Average pricing for a 5 lb parcel is $9.50. A fuel surcharge of 17.25% is standard as of June 2025.

5. SF Express

SF Express has built a niche as an international delivery powerhouse, especially for businesses working between China and San Francisco. Their Economy Express service is cost-effective, while their Standard Express handles rush delivery for global shipments.

Services & features:

• International freight and luggage delivery.

• Standard and Economy options.

• Reliable for legal documents and medical samples.

• Customizable logistics solutions with extensive support.

Rates: Base rates vary but typically start at $30 for international parcels. Delivery timelines range from 3 to 7 business days.

6. Reliable Couriers

For hyperlocal businesses, Reliable Couriers offers some of the most tailored courier services in San Francisco. From process serving to courtroom staging, they specialise in secure and fast deliveries within the city.

Services & features:

• Rush courier services for urgent legal deliveries.

• Regularly scheduled deliveries for hospitals and clinics.

• Direct routing and live tracking.

• Special handling for legal documents and sensitive cargo.

Rates: Quotes are customized. Most same-day deliveries start at $12 within city limits. You can request detailed rates online or by phone.

7. Uber Direct

Uber has extended its expertise in real-time location tracking into the courier space. Uber Direct helps San Francisco businesses schedule and deliver packages on demand using their existing fleet of delivery drivers.

Services & features:

• On-demand and scheduled delivery.

• Transparent pricing model based on speed and distance.

• Cargo van support for small business deliveries.

• Real-time package tracking.

Rates: Delivery starts around $6 and increases with distance. Ideal for businesses needing cost-effective delivery without platform commissions.

8. Senpex

Senpex is a tech-first courier company offering data-driven delivery solutions in San Francisco. Known for multi-stop route optimization, it is popular among retailers and healthcare clients needing precision.

Services & features:

• Medical sample and equipment deliveries.

• Multi-stop scheduling with route planning AI.

• Support for court filings and superior court services.

• 24/7 customer support and flexible pickup options.

Rates: Custom pricing available via their website. Quotes depend on service type, weight, and destination, but the cost-saving is noticeable due to their route optimization model.

Why smart businesses in San Francisco choose ClickPost?

Navigating the diverse courier landscape in the San Francisco Bay Area can be overwhelming, especially for growing businesses. ClickPost offers a single, integrated solution that connects you to multiple courier partners through one platform. With robust carrier aggregation, ClickPost helps you choose the best service for each order—be it same day, rush delivery, or legal courier needs.

ClickPost key features:

• Real-time courier tracking across multiple partners.

• Automated carrier allocation based on destination and service-level agreements.

• Seamless integration with e-commerce and ERP platforms.

• Custom dashboards to monitor delivery performance and returns.

• AI-powered insights for reducing delivery costs and delays.

ClickPost does more than manage deliveries; it builds intelligent logistics workflows that scale with your business. Whether you are sending medical samples to UCSF Medical Center or documents to the bankruptcy court, we simplify your delivery process.

Book a free demo today and make your San Francisco logistics operation future-ready.

Final deliveries: Wrapping up with purpose

Courier services in San Francisco are about moving business forward. In a city where every hour counts and every delivery reflects your brand’s reliability, choosing the right courier is a strategy. The delivery ecosystem here thrives on rapid adaptation, tech-driven precision, and trust. And with options ranging from legacy giants to local disruptors, the San Francisco delivery scene offers something for every client type—from the corner flower shop to a venture-backed tech firm.

As businesses prepare for the future, one thing is clear: delivery expectations will keep rising. Customers will demand more transparency, faster turnarounds, and ethical operations. In this climate, aligning with courier partners that deliver not just packages but also reliability, speed, and flexibility becomes a competitive edge. And with platforms like ClickPost guiding that journey, the road ahead looks streamlined, scalable, and sustainable.